Nuclear organization and silencing: putting things in their place

被引：47

作者：

Hediger, F ^{[1
]}

Gasser, SM ^{[1
]}

机构：

[1] Univ Geneva, Dept Mol Biol, CH-1211 Geneva 4, Switzerland

来源：

NATURE CELL BIOLOGY | 2002年 / 4卷 / 03期

关键词：

D O I：

10.1038/ncb0302-e53

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The positioning of a gene within the nucleus is thought to help regulate its transcriptional state. An example is yeast telomeres, which have a propensity to cluster at the nuclear periphery and suppress subtelomeric genes. With a membrane anchoring technique, new data indicate that there may be a second class of perinuclear silencing sites, which require pore-associated myosin-like proteins to establish repression.

引用

页码：E53 / E55

页数：3

共 20 条

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