Concurrent alkylation-methoxylation of 4,5-dihalopyridazin-6-ones and synthesis of 5-halo-4-hydroxypyridazin-6-ones

被引：34

作者：

Cho, SD ^{[1
]}

Choi, WY ^{[1
]}

Yoon, YJ ^{[1
]}

机构：

[1] GYEONGSANG NATL UNIV,RES INST NAT SCI,CHINJU 660701,SOUTH KOREA

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1996年 / 33卷 / 06期

关键词：

D O I：

10.1002/jhet.5570330605

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Alkyl-5-halo-4-methoxypyridazin-6-ones were synthesized from 1-alkyl-4,5-dihalopyridazin-6-ones by the concurrent alkylation-methoxylation. 1-Allryl-5-halo-4-hydroxypyridazin-6-ones were also prepared.

引用

页码：1579 / 1582

页数：4

共 10 条

[1] A MILD PROCEDURE FOR O-DEACYLATION OF THE FULLY ACYLATED SUGAR MOIETY OF NUCLEOSIDES IN THE PRESENCE OF CYANIDE [J].

ASAKURA, J ;

TOMURA, T .

NUCLEOSIDES & NUCLEOTIDES, 1988, 7 (02) :245-248

[2] A LARGE-SCALE SYNTHESIS OF 3-CHLORO-5-METHOXYPYRIDAZINE [J].

BRYANT, RD ;

KUNNG, FA ;

SOUTH, MS .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1995, 32 (05) :1473-1476

[3]

CHOI SY, 1990, B KOREAN CHEM SOC, V11, P228

[4]

DURY K, 1964, ANGEW CHEM INT EDIT, V4, P292

[5] UBER SULFANILAMIDO-PYRIDAZINE .1. HETEROCYCLISCHE SULFONAMIDE [J].

GRUNDMANN, C .

CHEMISCHE BERICHTE-RECUEIL, 1948, 81 (01) :1-11

[6]

LEE SG, 1989, B KOR CHEM SOC, V10, P317

[7] THE REACTION OF 2-SUBSTITUTED-4,5-DICHLORO-3(2H)-PYRIDAZINONES WITH ALKOXIDES AND ALKYLTHIOLATES [J].

LYGA, JW .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1988, 25 (06) :1757-1760

[8] MUCOCHLORIC ACID .2. REACTIONS OF THE ALDEHYDE GROUP [J].

MOWRY, DT .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1953, 75 (08) :1909-1910

[9] CHLOROPYRIDAZINES [J].

SCHONBECK, R ;

KLOIMSTE.E .

MONATSHEFTE FUR CHEMIE, 1968, 99 (01) :15-+

[10]

YAMADA T, 1981, SYNTHESIS-STUTTGART, P631

← 1 →