Tumor size and axillary metastasis, a correlative occurrence in 1244 cases of breast cancer between 1980 and 1995

A review of 1244 breast cancer cases from the Tumor Registry of Northwest Community Hospital between 1980 and 1995 was carried out to investigate the incidence of axillary metastasis, There were 442 patients (35.45%) with positive nodes, The small lesions were graded to ascertain if size and grade of small tumors can be used to predict axillary metastasis. One hundred and seventy-nine cases of less than or equal to 1.0 cm were retrospectively reviewed by one pathologist, Tumors <0.4 cm had negative nodes. Those with nuclear and histologic grades of 1 had 3% positive nodes, the remainder had positive nodes ranging from 11% to 19%, Infiltrating duct cancers of nuclear grade 3, histologic grade 2, and positive nodes, showed a 40% mortality, Eighteen patients died in the 0.5-1.0 cm tumor size range, mostly of histologic grade 2 and nuclear grade 3. Nuclear and histologic grade 1 tumors with infiltrating duet cancers had negative nodes and showed a good prognosis, Eased on this study, node dissection can be omitted in these patients and in those with tumors less than or equal to 0.4 cm, For all other lesions, full axillary node dissection and detailed pathologic examination is still the gold standard for evaluating the axilla.