Anti-depressant activities of Areca catechu fruit extract

被引：39

作者：

Dar, A

Khatoon, S

Rahman, G

AttaUrRahman

机构：

[1] H. E. J. Res. Institute of Chemistry, University of Karachi, Karachi

[2] H.E.J. Res. Institute of Chemistry, University of Karachi

来源：

PHYTOMEDICINE | 1997年 / 4卷 / 01期

关键词：

Areca catechu; hexane and aqueous fractions; immobility time; rat brain; monoamine oxidase inhibition;

D O I：

10.1016/S0944-7113(97)80026-8

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The hexane and aqueous fractions of Areca catechu (A. catechu) have demonstrated anti-depressant properties in screens used to detect such activity. Similar properties had previously been detected in the plant's aqueous ethanolic extract. The aqueous ethanolic extract (F-1), and the hexane (F-2) and aqueous (F-5) fractions inhibit monoamine oxidase (MAO) in rat brain homogenates. The aqueous fraction seems to be the most potent inhibitor of MAO and its effect is similar to that of clorgyline (a specific MAO-A inhibitor). The extract and fractions from A. catechu, therefore, merit further research in the quest for new anti-depressants.

引用

页码：41 / 45

页数：5

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