A new approach to the core of Roseophilin

被引：26

作者：

Fagan, MA ^{[1
]}

Knight, DW ^{[1
]}

机构：

[1] Cardiff Univ, Dept Chem, Cardiff CF10 3TB, S Glam, Wales

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 33期

基金：

英国工程与自然科学研究理事会;

关键词：

iodocyclisation; 5-endo-dig; pyrroles; radicals and radical reactions;

D O I：

10.1016/S0040-4039(99)01217-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Endo-dig iodocyclisation of the homopropargylic sulfonamide 10 gives the iodo-dihydropyrrole 11; subsequent 5-exo-trig radical cyclisation of the derived iodopyrrole 12 followed by allylic oxidation then delivers the bicyclic core 2 of Roseophilin 1. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：6117 / 6120

页数：4

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