Technical manual for manufacturing autologous fibrin tissue adhesive

被引：10

作者：

Park, JJ

Cintron, JR

Siedentop, KH

Orsay, CP

Pearl, RK

Nelson, RL

Abcarian, H

机构：

[1] VA Chicago Hlth Care Syst, W Side Div, Dept Surg, Chicago, IL 60612 USA

[2] Univ Illinois Hosp & Clin, Dept Surg, Chicago, IL USA

[3] Univ Illinois Hosp & Clin, Dept Otolaryngol, Chicago, IL USA

[4] Cook Cty Hosp, Dept Surg, Div Colon & Rectal Surg, Chicago, IL 60612 USA

来源：

DISEASES OF THE COLON & RECTUM | 1999年 / 42卷 / 10期

关键词：

fistula; autologous fibrin glue;

D O I：

10.1007/BF02234225

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

PURPOSE: The aim of this article is to provide a concise and simple technical manual for manufacturing autologous fibrin tissue adhesive derived from the precipitation of fibrinogen using a combination of ethanol and freezing for surgery. METHODS: AU materials and equipment needed to manufacture ethanol-based autologous fibrin tissue adhesive are Listed. In addition, step-by-step instructions are provided to allow for easy and rapid fibrin adhesive production. RESULTS: Ethanol-based autologous fibrin tissue adhesive can be manufactured in under 60 minutes. Furthermore, at our institution the startup cost for manufacturing ethanol-based autologous fibrin tissue adhesive was under $2,500.00. CONCLUSION: Ethanol-based autologous fibrin tissue adhesive is a safe, reliable, and easily manufactured autologous fibrin tissue adhesive that can be made by a trained technician in any blood bank, pharmacy, or surgical laboratory.

引用

页码：1334 / 1338

页数：5

共 10 条

[1] Postoperative bleeding induced by topical bovine thrombin: Report of two cases [J].