Even chromatin gets the blues

被引：10

作者：

Hyman, SE ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Neurobiol, Cambridge, MA 02138 USA

来源：

NATURE NEUROSCIENCE | 2006年 / 9卷 / 04期

关键词：

D O I：

10.1038/nn0406-465

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Antidepressants take a few weeks to act, and their effects can extend for months after the drugs are discontinued. Tsankova et al. suggest a possible molecular basis for these effects, by showing that stress and the antidepressant imipramine induce modifications of chromatin to produce more or less repressive states for gene expression.

引用

页码：465 / 466

页数：2

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