Disulfide bridges are not involved in penicillin-binding protein 1b dimerization in Escherichia coli

被引：10

作者：

Chalut, C

Remy, MH

Masson, JM

机构：

[1] IPBS, CNRS, F-31077 Toulouse, France

[2] Inst Natl Sci Appl, F-31077 Toulouse, France

来源：

JOURNAL OF BACTERIOLOGY | 1999年 / 181卷 / 09期

关键词：

D O I：

10.1128/JB.181.9.2970-2972.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

PBP1b can be found as a dimer in Escherichia coli. Previous results suggested that dimerization involved the cysteine(s) in an intermolecular disulfide bond. We show that either deletion mutants or a mutant without cysteines is fully active and still binds penicillin and that the latter can also form dimers.

引用

收藏

页码：2970 / 2972

页数：3

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