Screening for potential new probiotic based on probiotic properties and α-glucosidase inhibitory activity

被引：225

作者：

Chen, Pei ^{[1
]}

Zhang, Qiuxiang ^{[2
]}

Dang, Hui ^{[1
,3
]}

Liu, Xiaoming ^{[2
]}

Tian, Fengwei ^{[1
]}

Zhao, Jianxin ^{[1
]}

Chen, Yongquan ^{[2
]}

Zhang, Hao ^{[2
]}

Chen, Wei ^{[1
]}

机构：

[1] Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Peoples R China

[2] Jiangnan Univ, Sch Food Sci & Technol, Wuxi 214122, Peoples R China

[3] Shaanxi Normal Univ, Coll Food Engn & Nutr Sci, Xian 710062, Peoples R China

来源：

FOOD CONTROL | 2014年 / 35卷 / 01期

基金：

中国国家自然科学基金; 国家高技术研究发展计划(863计划);

关键词：

Lactic acid bacteria; Antioxidative; alpha-Glucosidase; Inhibitory activity; Caco-2; cells; LACTIC-ACID BACTERIA; LACTOBACILLUS-ACIDOPHILUS; OXIDATIVE STRESS; BILE-SALT; CHOLESTEROL; BIFIDOBACTERIUM; TOLERANCE; ADHESION;

D O I：

10.1016/j.foodcont.2013.06.027

中图分类号：

TS2 [食品工业];

学科分类号：

100403 [营养与食品卫生学];

摘要：

In this study, 11 lactic acid bacteria (LAB) strains were screened for potential new probiotics using in vitro methods, including acid and bile salt tolerance, adhesion, antioxidative and a-glucosidase inhibitory activity. The results indicated that Lactobacillus casei 2W and Lactobacillus rhamnosus Z7 showed better potential probiotic properties and a-glucosidase inhibitory activity in vitro. The characteristics of L. casei 2W were better than those of L rhamnosus GG, and L rhamnosus Z7 was the most similar strain to L rhamnosus GG, which had an antidiabetic capability. This finding suggested that L casei 2W and L rhamnosus Z7 could be used as potential antidiabetic probiotics. Further research is required to examine the a-glucosidase inhibitory activity of these strains. Crown Copyright (C) 2013 Published by Elsevier Ltd. All rights reserved.

引用

页码：65 / 72

页数：8

共 39 条

[1]

Superoxide dismutase plays an important role in the survival of Lactobacillus sake upon exposure to elevated oxygen [J].