Calcium as a versatile second messenger in the control of gene expression

被引：2

作者：

Hardingham, GE ^{[1
]}

Bading, H ^{[1
]}

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

MICROSCOPY RESEARCH AND TECHNIQUE | 1999年 / 46卷 / 06期

关键词：

CREB; transcription; CaM kinase; NFAT; NFkB;

D O I：

10.1002/(SICI)1097-0029(19990915)46:6<348::AID-JEMT3>3.0.CO;2-A

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The elevation of intracellular calcium is a major effector of stimulus-induced physiological change in a variety of cell types. Such change is invariably complex and frequently involves the activation of gene expression. Calcium signals are often able to activate different subsets of genes within the same cell, the basis for which has been unclear. Recent, studies have revealed that a number of differing properties of the calcium signal are responsible for distinct cellular responses. (C) 1999 Wiley-Liss, Inc.

引用

收藏

页码：348 / 355

页数：8

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