Omics of Cancer

被引:2
作者
Bhati, Aniruddha [1 ]
Garg, H. [1 ]
Gupta, A. [1 ]
Chhabra, H. [1 ]
Kumari, A. [1 ]
Patel, T. [1 ]
机构
[1] VIT, Sch BioSci & Technol, Div Med Biotechnol, Vellore, Tamil Nadu, India
关键词
Genomics; proteomics; epigenomics; transcriptomics; NUCLEOTIDE-SEQUENCE; HUMAN BREAST; GENOME; LUNG; PROTEOME;
D O I
10.7314/APJCP.2012.13.9.4229
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
With the advances in modern diagnostic expertise for cancer, certain approaches allowing scanning of the complete genome and the proteome are becoming very useful for researchers. These high throughput techniques have already proven power, over traditional detection methods, in differentiating disease sub-types and identifying specific genetic events during progression of cancer. This paper introduces major branches of omics-technology future possibilities of these methods in oncogenic detection.
引用
收藏
页码:4229 / 4233
页数:5
相关论文
共 41 条
[1]   Mutational analysis of the tyrosine kinome in colorectal cancers [J].
Bardelli, A ;
Parsons, DW ;
Silliman, N ;
Ptak, J ;
Szabo, S ;
Saha, S ;
Markowitz, S ;
Willson, JKV ;
Parmigiani, G ;
Kinzler, KW ;
Vogelstein, B ;
Velculescu, VE .
SCIENCE, 2003, 300 (5621) :949-949
[2]   Whole-genome re-sequencing [J].
Bentley, David R. .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 2006, 16 (06) :545-552
[3]   Identification of cancer genes by mutational profiling of tumor genomes [J].
Benvenuti, S ;
Arena, S ;
Bardelli, A .
FEBS LETTERS, 2005, 579 (08) :1884-1890
[4]   The mammalian epigenome [J].
Bernstein, Bradley E. ;
Meissner, Alexander ;
Lander, Eric S. .
CELL, 2007, 128 (04) :669-681
[5]   Perceptions of epigenetics [J].
Bird, Adrian .
NATURE, 2007, 447 (7143) :396-398
[6]   Somatic mutations affect key pathways in lung adenocarcinoma [J].
Ding, Li ;
Getz, Gad ;
Wheeler, David A. ;
Mardis, Elaine R. ;
McLellan, Michael D. ;
Cibulskis, Kristian ;
Sougnez, Carrie ;
Greulich, Heidi ;
Muzny, Donna M. ;
Morgan, Margaret B. ;
Fulton, Lucinda ;
Fulton, Robert S. ;
Zhang, Qunyuan ;
Wendl, Michael C. ;
Lawrence, Michael S. ;
Larson, David E. ;
Chen, Ken ;
Dooling, David J. ;
Sabo, Aniko ;
Hawes, Alicia C. ;
Shen, Hua ;
Jhangiani, Shalini N. ;
Lewis, Lora R. ;
Hall, Otis ;
Zhu, Yiming ;
Mathew, Tittu ;
Ren, Yanru ;
Yao, Jiqiang ;
Scherer, Steven E. ;
Clerc, Kerstin ;
Metcalf, Ginger A. ;
Ng, Brian ;
Milosavljevic, Aleksandar ;
Gonzalez-Garay, Manuel L. ;
Osborne, John R. ;
Meyer, Rick ;
Shi, Xiaoqi ;
Tang, Yuzhu ;
Koboldt, Daniel C. ;
Lin, Ling ;
Abbott, Rachel ;
Miner, Tracie L. ;
Pohl, Craig ;
Fewell, Ginger ;
Haipek, Carrie ;
Schmidt, Heather ;
Dunford-Shore, Brian H. ;
Kraja, Aldi ;
Crosby, Seth D. ;
Sawyer, Christopher S. .
NATURE, 2008, 455 (7216) :1069-1075
[7]   Dissecting DNA hypermethylation in cancer [J].
Estecio, Marcos R. H. ;
Issa, Jean-Pierre J. .
FEBS LETTERS, 2011, 585 (13) :2078-2086
[8]  
Feber A, 2010, CANCER GENET CYTOGEN, V203, P44
[9]   COMPLETE NUCLEOTIDE-SEQUENCE OF BACTERIOPHAGE MS2-RNA - PRIMARY AND SECONDARY STRUCTURE OF REPLICASE GENE [J].
FIERS, W ;
CONTRERAS, R ;
DUERINCK, F ;
HAEGEMAN, G ;
ISERENTANT, D ;
MERREGAERT, J ;
MINJOU, W ;
MOLEMANS, F ;
RAEYMAEKERS, A ;
VANDENBERGHE, A ;
VOLCKAERT, G ;
YSEBAERT, M .
NATURE, 1976, 260 (5551) :500-507
[10]   Mining the plasma proteome for cancer biomarkers [J].
Hanash, Samir M. ;
Pitteri, Sharon J. ;
Faca, Vitor M. .
NATURE, 2008, 452 (7187) :571-579