Further evaluation of a rapid diagnostic test for melioidosis in an area of endemicity

被引:28
作者
O'Brien, M
Freeman, K
Lum, G
Cheng, AC
Jacups, SP
Currie, BJ
机构
[1] Charles Darwin Univ, Menzies Sch Hlth Res, Casuarina, NT 0811, Australia
[2] Flinders Univ S Australia, No Terr Clin Sch, Darwin, NT, Australia
[3] Royal Darwin Hosp, Dept Pathol, Microbiol Lab, Darwin, NT, Australia
[4] Univ Melbourne, Fac Med, Melbourne, Vic, Australia
关键词
D O I
10.1128/JCM.42.5.2239-2240.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Immunochromatographic test (ICT) kits for the rapid detection of immunoglobulin G (IgG) and IgM antibodies to Burkholderia pseudomallei were compared to the indirect hemagglutination (IHA) assay. In 138 culture-confirmed melioidosis cases, sensitivities were 80, 77, and 88% for IIIA, ICT IgG, and ICT IgM, respectively. In a prospective study of 160 consecutive sera samples sent for melioidosis serology, respective specificities were 91, 90, and 69, positive predictive values were 41, 32, and 18, and negative predictive values were 99, 98, and 100%. ICT IgM kits are unreliable for diagnosis of melioidosis, but ICT IgG kits may be useful for diagnosing travelers presenting with possible melioidosis who return from regions where melioidosis is endemic.
引用
收藏
页码:2239 / 2240
页数:2
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