Protective effect of neuromonitoring during cardiac surgery

被引:47
作者
Edmonds, HL [1 ]
机构
[1] Neuromonitoring Associates Inc, Louisville, KY 40207 USA
来源
NEUROPROTECTIVE AGENTS | 2005年 / 1053卷
关键词
cardiac surgery; brain injury; neuroprotection; EEG; cerebral oximetry; transcranial Doppler ultrasound; outcome;
D O I
10.1196/annals.1344.002
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This study was a retrospective examination of the influence of multimodality neuromonitoring on the incidence of serious brain injury associated with a common type of adult cardiac surgery, coronary artery bypass grafting (CABG). Multichannel EEG, cerebral oximetry, and transcranial Doppler ultrasound were used to detect and correct imbalances in cerebral perfusion and oxygenation. Imbalances were detected in 59% of the cases and successfully corrected in all but 2%. In the absence of neuromonitoring, the expected incidence of serious brain injury is 6.1%. With neuromonitoring, the actual observed incidence was 3.0% (P = 0.03). The apparent improvement can be attributed primarily to a reduction in the number of nonembolic diffuse injuries.
引用
收藏
页码:12 / 19
页数:8
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