Forces in Tissue Morphogenesis and Patterning

被引：887

作者：

Heisenberg, Carl-Philipp ^{[1
]}

Bellaiche, Yohanns ^{[2
]}

机构：

[1] IST Austria, A-3400 Klosterneuburg, Austria

[2] Inst Curie, CNRS UMR3215, INSERM U934, F-75248 Paris 05, France

来源：

CELL | 2013年 / 153卷 / 05期

关键词：

PLANAR CELL POLARITY; LEFT-RIGHT ASYMMETRY; NEURAL-TUBE CLOSURE; LIGHT-SHEET MICROSCOPY; DORSAL CLOSURE; NODAL FLOW; E-CADHERIN; APICAL CONSTRICTION; ADHERENS JUNCTIONS; ACTOMYOSIN NETWORK;

D O I：

10.1016/j.cell.2013.05.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

During development, mechanical forces cause changes in size, shape, number, position, and gene expression of cells. They are therefore integral to any morphogenetic processes. Force generation by actin-myosin networks and force transmission through adhesive complexes are two self-organizing phenomena driving tissue morphogenesis. Coordination and integration of forces by long-range force transmission and mechanosensing of cells within tissues produce large-scale tissue shape changes. Extrinsic mechanical forces also control tissue patterning by modulating cell fate specification and differentiation. Thus, the interplay between tissue mechanics and biochemical signaling orchestrates tissue morphogenesis and patterning in development.

引用

收藏

页码：948 / 962

页数：15

相关论文

共 162 条

[1]

Biomechanical forces promote embryonic haematopoiesis [J].

Adamo, Luigi ;

Naveiras, Olaia ;

Wenzel, Pamela L. ;

McKinney-Freeman, Shannon ;

Mack, Peter J. ;

Gracia-Sancho, Jorge ;

Suchy-Dicey, Astrid ;

Yoshimoto, Momoko ;

Lensch, M. William ;

Yoder, Mervin C. ;

Garcia-Cardena, Guillermo ;

Daley, George Q. .

NATURE, 2009, 459 (7250) :1131-U120

[2]

Integrating force-sensing and signaling pathways in a model for the regulation of wing imaginal disc size [J].

Aegerter-Wilmsen, Tinri ;

Heimlicher, Maria B. ;

Smith, Alister C. ;

de Reuille, Pierre Barbier ;

Smith, Richard S. ;

Aegerter, Christof M. ;

Basler, Konrad .

DEVELOPMENT, 2012, 139 (17) :3221-3231

[3]

Exploring the effects of mechanical feedback on epithelial topology [J].

Aegerter-Wilmsen, Tinri ;

Smith, Alister C. ;

Christen, Alix J. ;

Aegerter, Christof M. ;

Hafen, Ernst ;

Basler, Konrad .

DEVELOPMENT, 2010, 137 (03) :499-506

[4]

Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila [J].

Aigouy, Benoit ;

Farhadifar, Reza ;

Staple, Douglas B. ;

Sagner, Andreas ;

Roeper, Jens-Christian ;

Juelicher, Frank ;

Eaton, Suzanne .

CELL, 2010, 142 (05) :773-786

[5]

Physical Mechanisms Shaping the Drosophila Dorsoventral Compartment Boundary [J].

Aliee, Maryam ;

Roeper, Jens-Christian ;

Landsberg, Katharina P. ;

Pentzold, Constanze ;

Widmann, Thomas J. ;

Juelicher, Frank ;

Dahmann, Christian .

CURRENT BIOLOGY, 2012, 22 (11) :967-976

[6]

A mathematical model for dorsal closure [J].

Almeida, Luis ;

Bagnerini, Patrizia ;

Habbal, Abderrahmane ;

Noselli, Stephane ;

Serman, Fanny .

JOURNAL OF THEORETICAL BIOLOGY, 2011, 268 (01) :105-119

[7]

Knowing the Boundaries: Extending the Differential Adhesion Hypothesis in Embryonic Cell Sorting [J].

Amack, Jeffrey D. ;

Manning, M. Lisa .

SCIENCE, 2012, 338 (6104) :212-215

[8]

Propagation of Dachsous-Fat Planar Cell Polarity [J].

Ambegaonkar, Abhijit A. ;

Pan, Guohui ;

Mani, Madhav ;

Feng, Yongqiang ;

Irvine, Kenneth D. .

CURRENT BIOLOGY, 2012, 22 (14) :1302-1308

[9]

The orientation of cell divisions determines the shape of Drosophila organs [J].

Baena-López, LA ;

Baonza, A ;

García-Bellido, A .

CURRENT BIOLOGY, 2005, 15 (18) :1640-1644

[10]

PTEN Controls Junction Lengthening and Stability during Cell Rearrangement in Epithelial Tissue [J].

Bardet, Pierre-Luc ;

Guirao, Boris ;

Paoletti, Camille ;

Serman, Fanny ;

Leopold, Valentine ;

Bosveld, Floris ;

Goya, Yuki ;

Mirouse, Vincent ;

Graner, Francois ;

Bellaiche, Yohanns .

DEVELOPMENTAL CELL, 2013, 25 (05) :534-546

← 1 2 3 4 5 6 7 8 9 10 →