Indium trichloride catalyzed one-step synthesis of α-amino nitriles by a three-component condensation of carbonyl compounds, amines and potassium cyanide

被引：128

作者：

Ranu, BC ^{[1
]}

Dey, SS ^{[1
]}

Hajra, A ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Dept Organ Chem, Kolkata 700032, W Bengal, India

来源：

TETRAHEDRON | 2002年 / 58卷 / 13期

关键词：

alpha-amino nitriles; one-pot three-component condensation; indium trichloride;

D O I：

10.1016/S0040-4020(02)00132-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and general method has been developed for the synthesis of alpha-aminonitriles by a one-pot three-component condensation of aldehydes or ketones, amines and potassium cyanide in THF in presence of a catalytic amount of indium trichloride. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2529 / 2532

页数：4

共 17 条

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