Caveats in hair analysis in chronic arsenic poisoning

被引:103
作者
Hindmarsh, JT [1 ]
机构
[1] Univ Ottawa, Ottawa Hosp, Div Biochem, Ottawa, ON K1H 8L6, Canada
[2] Univ Ottawa, Dept Pathol & Lab Med, Ottawa, ON K1H 8L6, Canada
关键词
trace elements; blood; urine; hair; arsenic; toxicology; neuropathy; skin lesions; electromyography;
D O I
10.1016/S0009-9120(01)00282-X
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
The diagnosis and evaluation of chronic arsenic poisoning remains a difficult task. Clinical indicators are crude measures, and electromyography adds little to the picture. Blood arsenic levels are transitory, however urine levels are useful for monitoring ongoing exposure, Hair arsenic is useful as a confirmatory feature in chronic arsenic poisoning provided external contamination by arsenic can be excluded. The distribution of arsenic in cross sections or along the length of a shaft of hair cannot distinguish external contamination from arsenic derived from ingestion. (C) 2002 The Canadian Society of Clinical Chemists. All rights reserved.
引用
收藏
页码:1 / 11
页数:11
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