Melatonin and its agonists: an update

被引：45

作者：

Arendt, Josephine ^{[1
]}

Rajaratnam, Shantha M. W. ^{[2
]}

机构：

[1] Univ Surrey, Sch Biomed & Mol Sci, Ctr Chronobiol, Surrey GU2 7XH, England

[2] Monash Univ, Sch Psychol Psychiat & Psychol Med, Clayton, Vic 3800, Australia

来源：

BRITISH JOURNAL OF PSYCHIATRY | 2008年 / 193卷 / 04期

关键词：

D O I：

10.1192/bjp.bp.108.050955

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The pineal hormone melatonin is able to shift the timing of circadian rhythms, including the sleep-wake cycle, and to promote sleep. Melatonin agonists with similar properties have therapeutic potential for the treatment of circadian rhythm sleep disorders. Depression is specifically targeted by agomelatine, which is also a serotonin-2C (5-HT2C) antagonist.

引用

页码：267 / 269

页数：3

共 18 条

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