Human tumor necrosis factor is a chemoattractant for the parasite Entamoeba histolytica

被引：44

作者：

Blazquez, S

Zimmer, C

Guigon, G

Olivo-Marin, JC

Guillén, N

Labruyère, E

机构：

[1] Inst Pasteur, INSERM, U389, Cell Biol Parasitism Unit, F-75724 Paris 15, France

[2] Inst Pasteur, Publ Hlth Platform, F-75724 Paris 15, France

来源：

INFECTION AND IMMUNITY | 2006年 / 74卷 / 02期

关键词：

D O I：

10.1128/IAI.74.2.1407-1411.2006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In an analysis of the molecular factors triggering amebiasis, we investigated the chemotaxis of Entamoeba histolytica toward tumor necrosis factor (TNF) in vitro, using quantitative imaging techniques. Our findings enabled us to propose a hitherto unknown role for TNF as a chemokinetic and chemoattractant agent for this parasite.

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页码：1407 / 1411

页数：5

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