Neuron-like tubular membranes made of diblock copolymer amphiphiles

被引:39
作者
Battaglia, G
Ryan, AJ
机构
[1] Univ Sheffield, Kroto Res Inst, Dept Mat Engn, Sheffield S3 7HQ, S Yorkshire, England
[2] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England
关键词
amphiphiles; block copolymers; myelins; self-assembly; vesicles;
D O I
10.1002/anie.200503334
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Implications for the nervous system: The formation of polymeric myelin structures was studied at the copolymer/water interface and then elaborated in a dispersed phase. Sun-like structures formed with a complex multilamellar core and a corona made of short myelins. Myelin growth is solvent-promoted, in a strong analogy to natural myelins, which have membranes with a higher proportion of fluidizing molecules such as cholesterol. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:2052 / 2056
页数:5
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