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Drug switching and virologic-based endpoints in trials of antiretroviral drugs for HIV infection

被引：19
作者：
Phillips, AN
Walker, AS
机构：
[1] UCL, Royal Free & Univ Coll Med Sch, Royal Free Ctr HIV Med, Dept Primary Care & Populat Sci, London NW3 2PF, England
[2] MRC, Clin Trials Unit, London, England
来源：
AIDS | 2004年 / 18卷 / 03期
关键词：
randomized controlled trials; HIV; virologic failure; endpoint; intention to treat; viral load;
D O I：
10.1097/00002030-200402200-00001
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
[No abstract available]
引用
收藏
页码：365 / 370
页数：6
相关论文
共 29 条
  • [1] [Anonymous], 1996, Lancet, V348, P283
  • [2] Babiker A, 2000, AIDS RES HUM RETROV, V16, P1123
  • [3] *BHVA WRIT COMM BE, 2003, HIV MED S, V4, P1
  • [4] *DEP HHS, GUID US ANT AG HIV I
  • [5] Design and analysis of clinical trials with a bivariate failure time endpoint, with application to AIDS Clinical Trials Group Study A5142
    DiRienzo, AG
    DeGruttola, V
    [J]. CONTROLLED CLINICAL TRIALS, 2003, 24 (02): : 122 - 134
  • [6] DRAGSTED U, J INFECT DIS, V188, P635
  • [7] Virologic and regimen termination surrogate end points in AIDS clinical trials
    Gilbert, PB
    DeGruttola, V
    Hammer, SM
    Kuritzkes, DR
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (06): : 777 - 784
  • [8] Intermittent and sustained low-level HIV viral rebound in patients receiving potent antiretroviral therapy
    Greub, G
    Cozzi-Lepri, A
    Ledergerber, B
    Staszewski, S
    Perrin, L
    Miller, V
    Francioli, P
    Furrer, H
    Battegay, M
    Vernazza, P
    Bernasconi, E
    Günthard, HF
    Hirschel, B
    Phillips, AN
    Telenti, A
    [J]. AIDS, 2002, 16 (14) : 1967 - 1969
  • [9] A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less
    Hammer, SM
    Squires, KE
    Hughes, MD
    Grimes, JM
    Demeter, LM
    Currier, JS
    Eron, JJ
    Feinberg, JE
    Balfour, HH
    Dayton, LR
    Chodakewitz, JA
    Fischl, MA
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (11) : 725 - 733
  • [10] A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter
    Hammer, SM
    Katzenstein, DA
    Hughes, MD
    Gundacker, H
    Schooley, RT
    Haubrich, RH
    Henry, WK
    Lederman, MM
    Phair, JP
    Niu, M
    Hirsch, MS
    Merigan, TC
    Blaschke, TF
    Simpson, D
    McLaren, C
    Rooney, J
    Salgo, M
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (15) : 1081 - 1090
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