Epidemiology of Ischemic Stroke

被引:77
作者
Favate, Albert S. [1 ]
Younger, David S. [1 ,2 ]
机构
[1] NYU, Dept Neurol, Sch Med, Div Neuroepidemiol, New York, NY 10016 USA
[2] NYU, Coll Global Publ Hlth, New York, NY USA
关键词
Stroke; Public health; Epidemiology; WHITE-MATTER HYPERINTENSITIES; GENOME-WIDE ASSOCIATION; MODERATE ALCOHOL-CONSUMPTION; PERIPHERAL-VASCULAR-DISEASE; CLINICAL-CARDIOLOGY-COUNCIL; ATRIAL-FIBRILLATION; MAGNETIC-RESONANCE; PHYSICAL-ACTIVITY; GENETIC-BASIS; RISK-FACTORS;
D O I
10.1016/j.ncl.2016.06.013
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
lschemic stroke is a heterogeneous multifactorial disorder recognized by the sudden onset of neurologic signs related directly to the sites of injury in the brain where the morbid process occurs. The evaluation of complex neurologic disorders, such as stroke, in which multiple genetic and epigenetic factors interact with environmental risk factors to increase the risk has been revolutionized by the genome-wide association studies (GWAS) approach. This article reviews salient aspects of ischemic stroke emphasizing the impact of neuroepidemiology and GWAS.
引用
收藏
页码:967 / +
页数:15
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