Mukaiyama-Michael reaction of cyclic ketene silyl acetals and enones. Importance of ring flexibility in electron transfer process

被引：9

作者：

Fujita, Y

Fukuzumi, S

Otera, J

机构：

[1] OSAKA UNIV,FAC ENGN,DEPT APPL CHEM,SUITA,OSAKA 565,JAPAN

[2] OKAYAMA UNIV SCI,DEPT APPL CHEM,OKAYAMA 700,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(97)00321-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Michael reaction of macrocyclic ketene silyl acetals or alpha-enones occurs smoothly under electron transfer conditions while the reaction of 6-membered analogs is more sluggish, indicating the importance of the ring flexibility to allow the alpha,beta-carbon-carbon bonds of both reaction components to rotate when the radical species are generated. (C) 1997 Elsevier Science Ltd.

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页码：2117 / 2120

页数：4

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