Recovering metabolic pathways via optimization

被引：29

作者：

Beasley, John E. ^{[1
]}

Planes, Francisco J.

机构：

[1] Brunel Univ, Uxbridge UB8 3PH, Middx, England

[2] CEIT, San Sebastian 20018, Spain

[3] Univ Navarra, TECNUN, San Sebastian 20018, Spain

来源：

BIOINFORMATICS | 2007年 / 23卷 / 01期

关键词：

D O I：

10.1093/bioinformatics/btl554

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Motivation: A metabolic pathway is a coherent set of enzyme catalysed biochemical reactions by which a living organism transforms an initial (source) compound into a final (target) compound. Some of the different metabolic pathways adopted within organisms have been experimentally determined. In this paper, we show that a number of experimentally determined metabolic pathways can be recovered by a mathematical optimization model.

引用

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页码：92 / 98

页数：7

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