VEGF therapy: a timely retreat

被引：7

作者：

Alfranca, Arantzazu ^{[1
]}

机构：

[1] CNIC, Dept Vasc Biol & Inflammat, Madrid 28029, Spain

来源：

CARDIOVASCULAR RESEARCH | 2009年 / 83卷 / 04期

关键词：

GENE-TRANSFER; SKELETAL-MUSCLE; LIMB ISCHEMIA; ANGIOGENESIS; NEOVASCULARIZATION; HIF-1-ALPHA; MODEL;

D O I：

10.1093/cvr/cvp228

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

收藏

页码：611 / 612

页数：2

相关论文

共 13 条

[1]

Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors [J].

Arsic, N ;

Zentilin, L ;

Zacchigna, S ;

Santoro, D ;

Stanta, G ;

Salvi, A ;

Sinagra, G ;

Giacca, M .

MOLECULAR THERAPY, 2003, 7 (04) :450-459

[2]

Angiogenesis in health and disease [J].

Carmeliet, P .

NATURE MEDICINE, 2003, 9 (06) :653-660

[3]

Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy [J].

Dor, Y ;

Djonov, V ;

Abramovitch, R ;

Itin, A ;

Fishman, GI ;

Carmeliet, P ;

Goelman, G ;

Keshet, E .

EMBO JOURNAL, 2002, 21 (08) :1939-1947

[4]

Vascular Endothelial Growth Factor-A and Platelet-Derived Growth Factor-B Combination Gene Therapy Prolongs Angiogenic Effects via Recruitment of Interstitial Mononuclear Cells and Paracrine Effects Rather Than Improved Pericyte Coverage of Angiogenic Vessels [J].

Korpisalo, Petra ;

Karvinen, Henna ;

Rissanen, Tuomas T. ;

Kilpijoki, Johanna ;

Marjomaki, Varpu ;

Baluk, Peter ;

McDonald, Donald M. ;

Cao, Yihai ;

Eriksson, Ulf ;

Alitalo, Kari ;

Yla-Herttuala, Seppo .

CIRCULATION RESEARCH, 2008, 103 (10) :1092-U71

[5]

Lee RJ, 2000, CIRCULATION, V102, P898

[6]

Growth factor-induced therapeutic angiogenesis and arteriogenesis in the heart -: gene therapy [J].

Markkanen, JE ;

Rissanen, TT ;

Kivelä, A ;

Ylä-Herttuala, S .

CARDIOVASCULAR RESEARCH, 2005, 65 (03) :656-664

[7]

Newly identified biologically active and proteolysis-resistant VEGF-A isoform VEGF111 is induced by genotoxic agents [J].

Mineur, Pierre ;

Colige, Alain C. ;

Deroanne, Christophe. F. ;

Dubail, Johanne ;

Kesteloot, Frederic ;

Habraken, Yvette ;

Noel, Agnes ;

Voo, Stefan ;

Waltenberger, Johannes ;

Lapiere, Charles M. ;

Nusgens, Betty V. ;

Lambert, Charles A. .

JOURNAL OF CELL BIOLOGY, 2007, 179 (06) :1261-1273

[8]

Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis [J].

Ozawa, CR ;

Banfi, A ;

Glazer, NL ;

Thurston, G ;

Springer, ML ;

Kraft, PE ;

McDonald, DM ;

Blau, HM .

JOURNAL OF CLINICAL INVESTIGATION, 2004, 113 (04) :516-527

[9]

Stabilized HIF-1α is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer [J].

Pajusola, K ;

Künnapuu, J ;

Vuorikoski, S ;

Soronen, J ;

André, H ;

Pereira, T ;

Korpisalo, P ;

Ylä-Herttuala, S ;

Poellinger, L ;

Alitalo, K .

FASEB JOURNAL, 2005, 19 (08) :1365-+

[10]

Constitutively active HIF-1α improves perfusion and arterial remodeling in an endovascular model of limb ischemia [J].

Patel, TH ;

Kimura, H ;

Weiss, CR ;

Semenza, GL ;

Hofmann, LV .

CARDIOVASCULAR RESEARCH, 2005, 68 (01) :144-154