Reactivity and selectivity of 1,3-diyn-6-enes in electrophilic transition metal-catalyzed reactions

被引：44

作者：

Cho, Eun Jin ^{[1
]}

Kim, Mansuk ^{[1
]}

Lee, Daesung ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 23期

关键词：

D O I：

10.1021/ol062335c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] 1,3-Diyne is an excellent source of alkynyl metal carbene species upon activation with an electrophilic metal catalyst. The products from this bond reorganization process suggest that the metal carbene species, generated from the preferential participation of an acetate over an alkene in the first step, undergo an efficient metallotropic [1,3]-shift followed by termination via cyclopropanation.

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页码：5413 / 5416

页数：4

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