Formation of tethered supported bilayers by vesicle fusion onto lipopolymer monolayers promoted by osmotic stress

被引：55

作者：

Seitz, M

Ter-Ovanesyan, E

Hausch, M

Park, CK

Zasadzinski, JA

Zentel, R

Israelachvili, JN ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem Engn, Santa Barbara, CA 93106 USA

[2] Berg Univ Wuppertal, Fachbereich Chem, D-42097 Wuppertal, Germany

[3] Berg Univ Wuppertal, Inst Mat Wissensch, D-42097 Wuppertal, Germany

来源：

LANGMUIR | 2000年 / 16卷 / 14期

关键词：

D O I：

10.1021/la9915771

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An evidence of tethered lipid bilayer formation by vesicle adsorption onto lipopolymer monolayers is studied using atomic force microscopy (AFM). Polymer hydration is found to be an important factor governing this process. It is found that hypotonic osmotic stress acting upon lipid vesicles stimulates their incorporation in homogeneous bilayers on polymeric substrates. The formation of multilamellar and more complex surface aggregates is prevented. The polymer-supported lipid membrane is indeed a thermodynamically stable structure which can self-organize after lipid is supplied to a polymer-supported monolayer in hydrophilic and saline environment.

引用

页码：6067 / 6070

页数：4

共 26 条

[1] PHYSICAL-PROPERTIES OF SINGLE PHOSPHOLIPID-BILAYERS ADSORBED TO MICRO GLASS-BEADS - A NEW VESICULAR MODEL SYSTEM STUDIED BY H-2-NUCLEAR MAGNETIC-RESONANCE [J].