Aurantosides D, E, and F:: New antifungal tetramic acid glycosides from the marine sponge Siliquariaspongia japonica

被引：49

作者：

Sata, NU

Matsunaga, S

Fusetani, N ^{[1
]}

van Soest, RWM

机构：

[1] Univ Tokyo, Grad Sch Agr & Life Sci, Lab Aquat Nat Prod Chem, Bunkyo Ku, Tokyo 1138657, Japan

[2] Univ Amsterdam, Inst Systemat & Ecol, NL-1090 GT Amsterdam, Netherlands

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 07期

关键词：

D O I：

10.1021/np9900021

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Aurantosides D-F (4-6), new polyene tetramic acids comprising an N-trisaccharide unit, have been isolated from the marine sponge Siliquariaspongia japonica. Their structures were determined by spectral and chemical methods. A reinvestigation of NMR data of the previously isolated aurantosides A and B led to revision of the geometry of the terminal. double bond. Aurantosides exhibit potent antifungal activity against Aspergillus fumigatus and Candida albicans.

引用

页码：969 / 971

页数：3

共 7 条

[1] ABSOLUTE AND RELATIVE CONFIGURATION OF ERYTHROSKYRIN [J].

BEUTLER, JA ;

HILTON, BD ;

CLARK, P ;

TEMPESTA, MS ;

CORLEY, DG .

JOURNAL OF NATURAL PRODUCTS, 1988, 51 (03) :562-566

[2]

Marshall J. L., 1983, CARBON CARBON CARBON, P33

[3] BIOACTIVE MARINE METABOLITES .38. AURANTOSIDE-A AND AURANTOSIDE-B - CYTOTOXIC TETRAMIC ACID GLYCOSIDES FROM THE MARINE SPONGE THEONELLA SP [J].

MATSUNAGA, S ;

FUSETANI, N ;

KATO, Y ;

HIROTA, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (25) :9690-9692

[4] Bioactive marine metabolites.: Part 87.: Rubrosides A-H, new bioactive tetramic acid glycosides from the marine sponge Siliquariaspongia japonica [J].

Sata, NU ;

Wada, S ;

Matsunaga, S ;

Watabe, S ;

van Soest, RWM ;

Fusetani, N .

JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (07) :2331-2339

[5]

SCHABACHER K, 1973, TETRAHEDRON LETT, P2691

[6]

WAKIMOTO T, IN PRESS BIOORG MED

[7] Aurantoside C, a new tetramic acid glycoside from the sponge Homophymia conferta [J].

Wolf, D ;

Schmitz, FJ ;

Qiu, F ;

Kelly-Borges, M .

JOURNAL OF NATURAL PRODUCTS, 1999, 62 (01) :170-172

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