High-throughput optofluidic platforms for mosaicked microfibers toward multiplex analysis of biomolecules

被引：37

作者：

Cho, Soojeong ^{[1
]}

Shim, Tae Soup ^{[1
]}

Yang, Seung-Man ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Natl Creat Res Initiat Ctr Integrated Optofluid S, Dept Chem & Biomol Engn, Taejon 305701, South Korea

来源：

LAB ON A CHIP | 2012年 / 12卷 / 19期

关键词：

FLOW LITHOGRAPHY; FABRICATION; PHOTOPOLYMERIZATION; FLUORESCENT; FIBERS;

D O I：

10.1039/c2lc40439g

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

We describe high-throughput optofluidic platforms for mosaic-patterned microfibers by generating stratified laminar flows. An inert carrier liquid flow near PDMS channel walls conveyed a photopolymerizable liquid which permitted stable production of microfibers with particular morphologies and compositional patterns. Finally, mosaicked microfibers were prepared with desired configurations toward multiplex biomolecular analysis.

引用

收藏

页码：3676 / 3679

页数：4

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[1]

Progress in the Field of Electrospinning for Tissue Engineering Applications [J].

Agarwal, Seema ;

Wendorff, Joachim H. ;

Greiner, Andreas .

ADVANCED MATERIALS, 2009, 21 (32-33) :3343-3351

[2]

Non-polydimethylsiloxane devices for oxygen-free flow lithography [J].

Bong, Ki Wan ;

Xu, Jingjing ;

Kim, Jong-Ho ;

Chapin, Stephen C. ;

Strano, Michael S. ;

Gleason, Karen K. ;

Doyle, Patrick S. .

NATURE COMMUNICATIONS, 2012, 3

[3]

Hydrodynamic Focusing Lithography [J].

Bong, Ki Wan ;

Bong, Ki Tae ;

Pregibon, Daniel C. ;

Doyle, Patrick S. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (01) :87-90

[4]

Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering [J].

Chung, Bong Geun ;

Lee, Kwang-Ho ;

Khademhosseini, Ali ;

Lee, Sang-Hoon .

LAB ON A CHIP, 2012, 12 (01) :45-59

[5]

Continuous-flow lithography for high-throughput microparticle synthesis [J].

Dendukuri, D ;

Pregibon, DC ;

Collins, J ;

Hatton, TA ;

Doyle, PS .

NATURE MATERIALS, 2006, 5 (05) :365-369

[6]

Modeling of Oxygen-Inhibited Free Radical Photopolymerization in a PDMS Microfluidic Device [J].

Dendukuri, Dhananjay ;

Panda, Priyadarshi ;

Haghgooie, Ramin ;

Kim, Ju Min ;

Hatton, T. Alan ;

Doyle, Patrick S. .

MACROMOLECULES, 2008, 41 (22) :8547-8556

[7]

Long-term in vivo glucose monitoring using fluorescent hydrogel fibers [J].

Heo, Yun Jung ;

Shibata, Hideaki ;

Okitsu, Teru ;

Kawanishi, Tetsuro ;

Takeuchi, Shoji .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (33) :13399-13403

[8]

Hydrodynamic spinning of hydrogel fibers [J].

Hu, Min ;

Deng, Rensheng ;

Schumacher, Karl M. ;

Kurisawa, Motoichi ;

Ye, Hongye ;

Purnamawati, Kristy ;

Ying, Jackie Y. .

BIOMATERIALS, 2010, 31 (05) :863-869

[9]

Inducing local T cell apoptosis with anti-Fas-functionalized polymeric coatings fabricated via surface-initiated photopolymerizations [J].

Hume, Patrick S. ;

Anseth, Kristi S. .

BIOMATERIALS, 2010, 31 (12) :3166-3174

[10]

Microfluidic chip-based fabrication of PLGA microfiber scaffolds for tissue engineering [J].

Hwang, Chang Mo ;

Khademhosseini, Ali ;

Park, Yongdoo ;

Sun, Kyung ;

Lee, Sang-Hoon .

LANGMUIR, 2008, 24 (13) :6845-6851