Restorative proctocolectomy for distal ulcerative colitis

被引:29
作者
Brunel, M [1 ]
Penna, C [1 ]
Tiret, E [1 ]
Balladur, P [1 ]
Parc, R [1 ]
机构
[1] Hop St Antoine, Serv Chirurg Digest, Dept Alimentary Tract Surg, F-75012 Paris, France
关键词
proctocolectomy; ulcerative colitis; bowel; quality of life;
D O I
10.1136/gut.45.4.542
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background-Chronic distal colitis may cause troublesome symptoms and alter quality of life. When medical treatment fails to control symptoms, patients and doctors are often reluctant to consider surgical resection because of the relatively small portion of the large bowel affected by the disease. Aim-To assess the outcome of restorative proctocolectomy (RP) in patients with distal colitis who required surgery for chronic debilitating symptoms and failed medical management. Patients/Methods-From 1986 to 1996, of 263 patients receiving RP for ulcerative colitis, 27 (16 men) were operated on for distal ulcerative colitis limited to the rectum and sigmoid colon. Bowel function and quality of life were compared before and one year after RP. Results-The mean (SD) duration of ulcerative colitis was 11 (6) years. RP was performed at a mean age of 46 (10) years. All the pouches were J-shaped, and a diverting loop ileostomy was always performed. Mean (SD) hospital stay was 25 (10) days. Seven complications occurred in six patients. Previously unknown severe dysplasia was discovered on the colectomy specimen in two patients. After RP there was a significant decrease in mean (SD) daytime stool frequency (8.2 (4) v 4.7 (2), p < 0.05), night-time stool frequency (2 (2) v 1 (1), p = 0.05), and the number of patients with urgency to defecate (26/27 v 1/27, p < 0.001). Sex life was improved in eight patients, social life in 26, and professional life in eight. Twenty six patients were satisfied with the results, and 25 wished that they had received surgery earlier in the course of their disease. Conclusion-RP can improve bowel function and quality of life in patients with disabling chronic symptoms of distal ulcerative colitis.
引用
收藏
页码:542 / 545
页数:4
相关论文
共 10 条
[1]   ILEAL POUCH-ANAL ANASTOMOSES COMPLICATIONS AND FUNCTION IN 1005 PATIENTS [J].
FAZIO, VW ;
ZIV, Y ;
CHURCH, JM ;
OAKLEY, JR ;
LAVERY, IC ;
MILSOM, JW ;
SCHROEDER, TK .
ANNALS OF SURGERY, 1995, 222 (02) :120-127
[2]   MEDICAL THERAPY OF ULCERATIVE-COLITIS [J].
HANAUER, SB .
LANCET, 1993, 342 (8868) :412-417
[3]  
LENNARDJONES JE, 1983, SCAND J GASTROENTERO, V18, P48
[4]   RESTORATIVE PROCTOCOLECTOMY - THE POUCH OPERATION - GOOD OR BAD [J].
MORTENSEN, N .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1992, 27 :130-135
[5]   QUALITY OF LIFE AFTER BROOKE ILEOSTOMY AND ILEAL POUCH ANAL ANASTOMOSIS - COMPARISON OF PERFORMANCE STATUS [J].
PEMBERTON, JH ;
PHILLIPS, SF ;
READY, RR ;
ZINSMEISTER, AR ;
BEAHRS, OH .
ANNALS OF SURGERY, 1989, 209 (05) :620-628
[6]   ILEAL POUCH-ANAL ANASTOMOSIS FOR CHRONIC ULCERATIVE-COLITIS - LONG-TERM RESULTS [J].
PEMBERTON, JH ;
KELLY, KA ;
BEART, RW ;
DOZOIS, RR ;
WOLFF, BG ;
ILSTRUP, DM .
ANNALS OF SURGERY, 1987, 206 (04) :504-513
[7]   QUALITY-OF-LIFE AFTER RESTORATIVE PROCTOCOLECTOMY WITH A PELVIC ILEAL RESERVOIR COMPARES FAVORABLY WITH THAT OF PATIENTS WITH MEDICALLY TREATED COLITIS [J].
SAGAR, PM ;
LEWIS, W ;
HOLDSWORTH, PJ ;
JOHNSTON, D ;
MITCHELL, C ;
MACFIE, J .
DISEASES OF THE COLON & RECTUM, 1993, 36 (06) :584-592
[8]   Outcome of restorative proctocolectomy with ileal reservoir for ulcerative colitis: Comparison of distal colitis with more proximal disease [J].
Samarasekera, DN ;
Stebbing, JF ;
Kettlewell, MGW ;
Jewell, DP ;
Mortensen, NJM .
GUT, 1996, 38 (04) :574-577
[9]   FAILURE OF RIGHT-SIDED COLOANAL ANASTOMOSIS FOR TREATMENT OF LEFT-SIDED ULCERATIVE-COLITIS - REPORT OF A CASE [J].
SCHWARZ, RJ ;
PEZIM, ME .
DISEASES OF THE COLON & RECTUM, 1991, 34 (07) :618-621
[10]   MUCOSAL PROCTECTOMY AND COLOANAL ANASTOMOSIS FOR DISTAL ULCERATIVE PROCTOCOLITIS [J].
VARMA, JS ;
BROWNING, GGP ;
SMITH, AN ;
SMALL, WP ;
SIRCUS, W .
BRITISH JOURNAL OF SURGERY, 1987, 74 (05) :381-383