Mathematical modeling of biological systems

被引:85
作者
Motta, Santo [1 ]
Pappalardo, Francesco [2 ]
机构
[1] Univ Catania, Dept Math & Comp Sci, Fac Pharm, I-95125 Catania, Italy
[2] Univ Catania, I-95125 Catania, Italy
关键词
mathematical biology; computational models; systems biology; BINDING PREDICTION SERVERS; SOFTWARE;
D O I
10.1093/bib/bbs061
中图分类号
Q5 [生物化学];
学科分类号
070307 [化学生物学];
摘要
Mathematical and computational models are increasingly used to help interpret biomedical data produced by high-throughput genomics and proteomics projects. The application of advanced computer models enabling the simulation of complex biological processes generates hypotheses and suggests experiments. Appropriately interfaced with biomedical databases, models are necessary for rapid access to, and sharing of knowledge through data mining and knowledge discovery approaches.
引用
收藏
页码:411 / 422
页数:12
相关论文
共 38 条
[1]
Combining cellular automata and lattice Boltzmann method to model multiscale avascular tumor growth coupled with nutrient diffusion and immune competition [J].
Alemani, Davide ;
Pappalardo, Francesco ;
Pennisi, Marzio ;
Motta, Santo ;
Brusic, Vladimir .
JOURNAL OF IMMUNOLOGICAL METHODS, 2012, 376 (1-2) :55-68
[2]
[Anonymous], 2009, SYSTEM
[3]
[Anonymous], 2007, NETWORKS
[4]
Immune System Network and Cancer Vaccine [J].
Bianca, Carlo ;
Pennisi, Marzio ;
Motta, Santo ;
Ragusa, Maria Alessandra .
NUMERICAL ANALYSIS AND APPLIED MATHEMATICS ICNAAM 2011: INTERNATIONAL CONFERENCE ON NUMERICAL ANALYSIS AND APPLIED MATHEMATICS, VOLS A-C, 2011, 1389 :945-948
[5]
MATHEMATICAL MODELING FOR KELOID FORMATION TRIGGERED BY VIRUS: MALIGNANT EFFECTS AND IMMUNE SYSTEM COMPETITION [J].
Bianca, Carlo .
MATHEMATICAL MODELS & METHODS IN APPLIED SCIENCES, 2011, 21 (02) :389-419
[6]
Identifying co-targets to fight drug resistance based on a random walk model [J].
Chen, Liang-Chun ;
Yeh, Hsiang-Yuan ;
Yeh, Cheng-Yu ;
Arias, Carlos Roberto ;
Soo, Von-Wun .
BMC SYSTEMS BIOLOGY, 2012, 6
[7]
A Periodically-Forced Mathematical Model for the Seasonal Dynamics of Malaria in Mosquitoes [J].
Chitnis, Nakul ;
Hardy, Diggory ;
Smith, Thomas .
BULLETIN OF MATHEMATICAL BIOLOGY, 2012, 74 (05) :1098-1124
[8]
Ghosh S, 2011, NONLINEAR ANAL-REAL, V12, P821
[9]
Software for systems biology: from tools to integrated platforms [J].
Ghosh, Samik ;
Matsuoka, Yukiko ;
Asai, Yoshiyuki ;
Hsin, Kun-Yi ;
Kitano, Hiroaki .
NATURE REVIEWS GENETICS, 2011, 12 (12) :821-832
[10]
Haefner J.W., 2005, Modeling biological systems: principles and applications