Effect of eiconol enriched with ω-3 polyunsaturated fatty acids on rat behavior and alcohol motivation

被引：2

作者：

Isaev, VA ^{[1
]}

Danilova, RA ^{[1
]}

Kushnir, EA ^{[1
]}

Lovat, ML ^{[1
]}

Ashmarin, IP ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Biol, Moscow 117234, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2001年 / 131卷 / 05期

关键词：

eiconol; polyunsaturated fatty acids; behavior; alcohol motivation; rats;

D O I：

10.1023/A:1017976031955

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We evaluated the effect of eiconol containing polyunsaturated fatty acids on the behavior and alcohol motivation in rats. Administration of eiconol for 10 days to alcoholized rats against the background of ethanol deprivation produced a sustained suppression of alcohol motivation and corrected deprivation-specific behavior.

引用

页码：461 / 463

页数：3

共 12 条

[1] α-linolenic acid deficiency modifies distractibility but not anxiety and locomotion in rats during aging [J].

Belzung, C ;

Leguisquet, AM ;

Barreau, S ;

Delion-Vancassel, S ;

Chalon, S ;

Durand, G .

JOURNAL OF NUTRITION, 1998, 128 (09) :1537-1542

[2]

Burov YV, 1985, NEUROCHEMISTRY PHARM

[3]

Carrié I, 2000, J LIPID RES, V41, P473

[4] Dietary fish oil affects monoaminergic neurotransmission and behavior in rats [J].

Chalon, S ;

Delion-Vancassel, S ;

Belzung, C ;

Guilloteau, D ;

Leguisquet, AM ;

Besnard, JC ;

Durand, G .

JOURNAL OF NUTRITION, 1998, 128 (12) :2512-2519

[5] EFFECTS OF AN OIL ENRICHED IN GAMMA-LINOLENIC ACID ON LOCOMOTOR-ACTIVITY AND BEHAVIOR IN THE MORRIS MAZE, FOLLOWING INUTERO ETHANOL EXPOSURE IN RATS [J].

DUFFY, O ;

MENEZ, JF ;

LEONARD, BE .

DRUG AND ALCOHOL DEPENDENCE, 1992, 30 (01) :65-70

[6] Chronic dietary n-3 polyunsaturated fatty acids deficiency affects the fatty acid composition of plasmenylethanolamine and phosphatidylethanolamine differently in rat frontal cortex, striatum, and cerebellum [J].

Favrelière, S ;

Barrier, L ;

Durand, G ;

Chalon, S ;

Tallineau, C .

LIPIDS, 1998, 33 (04) :401-407

[7]

Gerwick WH, 1997, ADV EXP MED BIOL, V407, P329

[8]

Isaev V. A., 2000, Fiziologiya Cheloveka, V26, P99

[9]

Raygada M, 1998, J NUTR, V128, P2505

[10] Modulation of learning and neuronal membrane composition in the rat by essential fatty acid preparation: Time-course analysis [J].

Yehuda, S ;

Bainovitz, S ;

Mostofsky, DI .

NEUROCHEMICAL RESEARCH, 1998, 23 (05) :627-634

← 1 2 →