Intracellularly degradable polyelectrolyte microcapsules

被引：267

作者：

De Geest, BG

Vandenbroucke, RE

Guenther, AM

Sukhorukov, GB

Hennink, WE

Sanders, NN

Demeester, J

De Smedt, SC

机构：

[1] Univ Ghent, Fac Pharmaceut Sci, Gen Biochem & Phys Pharm Labs, B-9000 Ghent, Belgium

[2] Max Planck Inst Colloids & Interfaces, D-14476 Potsdam, Germany

[3] Univ London Queen Mary Coll, IRC Mat, London E1 4NS, England

[4] Univ Utrecht, Utrecht Inst Pharmaceut Sci, NL-3508 TB Utrecht, Netherlands

来源：

ADVANCED MATERIALS | 2006年 / 18卷 / 08期

关键词：

D O I：

10.1002/adma.200502128

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Intracellular uptake and degradation of polyelectrolyte capsules is reported in this work. Two types of intracellular degradable capsules are described: enzyme-sensitive and hydrolysis-sensitive capsules (see figure). The results may be a significant step towards the biomedical application of polyelectrolyte capsules.

引用

页码：1005 / +

页数：6

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