B to A transition of DNA on the nanosecond time scale

被引：91

作者：

Yang, LQ ^{[1
]}

Pettitt, BM ^{[1
]}

机构：

[1] UNIV HOUSTON, DEPT CHEM, HOUSTON, TX 77204 USA

来源：

JOURNAL OF PHYSICAL CHEMISTRY | 1996年 / 100卷 / 07期

关键词：

D O I：

10.1021/jp953080f

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A 3.5-ns atomic-level computer simulation of a DNA solution was performed. We found that a dodecamer of DNA, which contains the recognition site for Eco RI endonuclease, transforms from B-form to A-form in 0.45 M salt water. This supports an earlier proposal on the A-DNA binding site for transcription factor IIIA.

引用

收藏

页码：2564 / 2566

页数：3

相关论文

共 33 条

[1]

ABOULELA F, 1988, NUCLEIC ACIDS RES, V16, P3559

[2]

Allen M. P., 1987, Computer Simulation of Liquids

[3] MOLECULAR CONFORMATIONS AND STRUCTURE TRANSITIONS OF RNA COMPLEMENTARY HELICES AND THEIR POSSIBLE BIOLOGICAL SIGNIFICANCE [J].

ARNOTT, S ;

FULLER, W ;

HODGSON, A ;

PRUTTON, I .

NATURE, 1968, 220 (5167) :561-&

[4]

BECKER MM, 1989, J BIOL CHEM, V264, P4163

[5] CHARMM - A PROGRAM FOR MACROMOLECULAR ENERGY, MINIMIZATION, AND DYNAMICS CALCULATIONS [J].

BROOKS, BR ;

BRUCCOLERI, RE ;

OLAFSON, BD ;

STATES, DJ ;

SWAMINATHAN, S ;

KARPLUS, M .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 1983, 4 (02) :187-217

[6] MOLECULAR-DYNAMICS SIMULATIONS ON SOLVATED BIOMOLECULAR SYSTEMS - THE PARTICLE MESH EWALD METHOD LEADS TO STABLE TRAJECTORIES OF DNA, RNA, AND PROTEINS [J].

CHEATHAM, TE ;

MILLER, JL ;

FOX, T ;

DARDEN, TA ;

KOLLMAN, PA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (14) :4193-4194

[7] DEFINITIONS AND NOMENCLATURE OF NUCLEIC-ACID STRUCTURE PARAMETERS [J].

DIEKMANN, S .

JOURNAL OF MOLECULAR BIOLOGY, 1989, 205 (04) :787-791

[8] STRUCTURE OF A B-DNA DODECAMER - CONFORMATION AND DYNAMICS .1. [J].

DREW, HR ;

WING, RM ;

TAKANO, T ;

BROKA, C ;

TANAKA, S ;

ITAKURA, K ;

DICKERSON, RE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (04) :2179-2183

[9] THE DNA-BINDING SITE OF THE XENOPUS TRANSCRIPTION FACTOR-IIIA HAS A NON-B-FORM STRUCTURE [J].

FAIRALL, L ;

MARTIN, S ;

RHODES, D .

EMBO JOURNAL, 1989, 8 (06) :1809-1817

[10] INFRARED LINEAR DICHROISM STUDIES OF DNA DRUG COMPLEXES - QUANTITATIVE-DETERMINATION OF THE DRUG-INDUCED RESTRICTION OF THE B-A TRANSITION [J].

FRITZSCHE, H .

NUCLEIC ACIDS RESEARCH, 1994, 22 (05) :787-791

← 1 2 3 4 →