Evaluation of hepatoprotective activity of Cassia fistula leaf extract

被引：73

作者：

Bhakta, T

Mukherjee, PK

Mukherjee, K

Banerjee, S

Mandal, SC

Maity, TK

Pal, M

Saha, BP ^{[1
]}

机构：

[1] Jadavpur Univ, Fac Engn & Technol, Dept Pharmaceut Technol, Kolkata 700032, W Bengal, India

[2] JSS Coll Pharm, Ootacamund 643001, TN, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1999年 / 66卷 / 03期

关键词：

Cassia fistula; n-heptane extract; SGOT; SGPT; alkaline phosphatase; bilirubin; carbon tetrachloride; liquid paraffin; hepatoprotective;

D O I：

10.1016/S0378-8741(98)00220-7

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Hepatoprotective activity of the n-heptane extract of Cassia fistula leaves was investigated in rats by inducing hepatotoxicity with carbon tetrachloride:liquid paraffin (1:1). The extract has been shown to possess significant protective effect by lowering the serum levels of transminases (SGOT and SGPT), bilirubin and alkaline phosphatase (ALP). The extract of C. fistula at a dose of 400 mg/kg showed significant hepatoprotective activity which was comparable to that of a standard hepatoprotective agent. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：277 / 282

页数：6

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