Room temperature ring-opening metathesis of pyridines by a transient TiC linkage

被引：75

作者：

Bailey, Brad C.

Fan, Hongjun

Huffman, John C.

Baik, Mu-Hyun ^{[1
]}

Mindiola, Daniel J.

机构：

[1] Indiana Univ, Ctr Mol Struct, Dept Chem, Bloomington, IN 47405 USA

[2] Indiana Univ, Sch Informat, Bloomington, IN 47405 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 21期

关键词：

D O I：

10.1021/ja061590p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The transient titanium alkylidyne complex (PNP)Ti≡CtBu (PNP = N[2-P(CHMe2)2-4-methylphenyl]2-), prepared from α-hydrogen abstraction of the corresponding alkylidene-alkyl species (PNP)Ti=CHtBu(CH2tBu), can readily cleave the C - N bond of N-heterocycles such as pyridine and 4-picoline at room temperature to afford azametallabicyclic systems. Experimental and theoretical studies strongly favor a ring-opening metathesis pathway where [2 + 2] cycloaddition of pyridine across the Ti≡C linkage ultimately leads to C - N bond rupture. Copyright © 2006 American Chemical Society.

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页码：6798 / 6799

页数：2

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