Agelasines J, K, and L from the Solomon Islands marine sponge Agelas cf. mauritiana

被引：46

作者：

Appenzeller, Jerome ^{[1
]}

Mihci, Ghezala ^{[1
]}

Martin, Marie-Therese ^{[1
]}

Gallard, Jean-Francois ^{[1
]}

Menou, Jean-Louis

Boury-Esnalllt, Nicole ^{[2
]}

Hooper, John ^{[3
]}

Petek, Sylvain

Chevalley, Severine ^{[4
]}

Valentin, Alexis ^{[4
]}

Zaparucha, Anne ^{[1
,4
]}

Al-Mourabit, Ali ^{[1
]}

Debitus, Cecile ^{[4
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

[2] CNRS, Marine Endoume Stn, Ctr Noumea, BPA5, F-13007 Marseille, France

[3] Queensland Museum, Brisbane, Qld 4101, Australia

[4] Univ Toulouse 3, Fac Pharmaceut Sci, IRD, UMR 152, F-31062 Toulouse 9, France

来源：

JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 08期

关键词：

D O I：

10.1021/np800212g

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new diterpene alkaloids, agelasine J (3), agelasine K (4), and agelasine L (5), were isolated from the marine sponge Agelas cf. mauritiana collected in the Solomon Islands. The structures of these compounds were elucidated by physical data analyses. They displayed in vitro antimalarial activity against Plasmodium falciparum.

引用

页码：1451 / 1454

页数：4

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