Organotin(IV)n+ complexes formed with biologically active ligands:: equilibrium and structural studies, and some biological aspects

The organotin(IV) cations form complexes with ligands containing {0}, {N}, {S}, or {phosphorus(O)} donor atoms with various composition and stability. The emergence of new experimental techniques (EXAFS, multinuclear H-1-, C-13-, Sn-119-NMR, Sn-119 Mossbauer, etc., spectroscopic techniques) provided useful information about the structure and stabilities of the complexes formed. We reviewed the literature on these type of complexes taking into account the biological aspects of the complexes discussed. (C) 2002 Elsevier Science B.V. All rights reserved.