Genomic and antigenic characterization of Jos virus

被引：17

作者：

Bussetti, Ana Valeria ^{[1
,2
]}

Palacios, Gustavo ^{[1
,2
]}

da Rosa, Amelia Travassos ^{[3
]}

Savji, Nazir ^{[1
,2
]}

Jain, Komal ^{[1
,2
]}

Guzman, Hilda ^{[3
]}

Hutchison, Stephen ^{[4
]}

Popov, Vsevolod L. ^{[3
]}

Tesh, Robert B. ^{[3
]}

Lipkin, W. Ian ^{[1
,2
]}

机构：

[1] Columbia Univ, Mailman Sch Publ Hlth, Ctr Infect & Immun, New York, NY 10027 USA

[2] Columbia Univ, WHO Collaborating Ctr Diagnost Surveillance & Imm, New York, NY USA

[3] Univ Texas Med Branch, Dept Pathol, Ctr Biodef & Emerging Infect Dis, Galveston, TX USA

[4] Roche Co, Life Sci 454, Branford, CT USA

来源：

JOURNAL OF GENERAL VIROLOGY | 2012年 / 93卷

基金：

美国国家卫生研究院;

关键词：

HIDDEN MARKOV MODEL; VALLEY FEVER VIRUS; THOGOTO-VIRUS; TICK-BORNE; PROTEIN; RNA; PREDICTION; SEQUENCE; IDENTIFICATION; NUCLEOPROTEIN;

D O I：

10.1099/vir.0.035121-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Jos virus (JOSV), originally isolated in Jos, Nigeria in 1967, has remained unclassified despite cultivation in tissue culture, development of animal models of infection and implementation of seroprevalence surveys for infection. Here, we report genetic, ultrastructural and serological evidence that JOSV is an orthomyxovirus distinct from but phylogenetically related to viruses of the genus Thogotovirus.

引用

页码：293 / 298

页数：6

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