The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region

被引：29

作者：

Lee, Crystal Man Ying ^{[1
]}

Huxley, Rachel R. ^{[1
]}

Woodward, Mark ^{[2
]}

Zimmet, Paul ^{[3
]}

Shaw, Jonathan ^{[3
]}

Cho, Nam H. ^{[4
]}

Kim, Hyung Rae ^{[5
]}

Viali, Satu

Tominaga, Makoto ^{[6
]}

Vistisen, Dorte ^{[7
]}

Borch-Johnsen, Knut ^{[7
]}

Colagiuri, Stephen ^{[8
]}

机构：

[1] Univ Sydney, George Inst Int Hlth, Sydney, NSW 2050, Australia

[2] Mt Sinai Med Ctr, Dept Med, New York, NY 10029 USA

[3] Int Diabet Inst, Melbourne, Vic, Australia

[4] Ajou Univ, Sch Med & Hosp, Suwon 441749, South Korea

[5] Korean Natl Inst Hlth, Ctr Genome Sci, Seoul, South Korea

[6] Yamagata Univ, Yamagata 990, Japan

[7] Steno Diabet Ctr, Copenhagen, Denmark

[8] Univ Sydney, Inst Obes Nutr & Exercise, Sydney, NSW 2050, Australia

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 2008年 / 81卷 / 03期

基金：

英国医学研究理事会;

关键词：

metabolic syndrome; abdominal obesity; Asia-Pacific;

D O I：

10.1016/j.diabres.2008.05.011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: To compare the prevalence of metabolic syndrome (MetS) by combinations of MetS components derived from the National Cholesterol Education Program Adult Treatment Panel III (ATPIII) and International Diabetes Federation (IDF) definitions. Methods: Four studies with ethnically distinct populations from the Asia-Pacific region were selected from the DETECT-2 study database. The prevalences of combinations of MetS components using the modified ATPIII (modATPIII) and IDF MetS definitions were compared between sexes and across populations. Results: A total of 22,952 participants from Australia, Japan, Korea and Samoa were included. The age-adjusted prevalence of modATPIII MetS varied from 9.4 to 35.8% in men and 10.3 to 57.2% in women; results for IDF were generally higher. Prevalences of the 16 possible MetS component combinations from the modATPIII definition that result in a diagnosis of MetS ranged from 0 to 12.7%. Of those with IDF-defined abdominal obesity, the prevalences of the 11 IDF-defined MetS component combinations ranged from 0.2 to 18.3%. Conclusions: The large variation in the prevalence of possible MetS component combinations to diagnose MetS may explain the different risk of cardiovascular outcomes associated with MetS in different populations, especially since particular combinations of MetS components are associated with different risk of cardiovascular disease. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：377 / 380

页数：4

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