Choroidal neovascularization

被引：450

作者：

Grossniklaus, HE

Green, WR

机构：

[1] Emory Univ, Sch Med, Dept Ophthalmol, Atlanta, GA 30322 USA

[2] Emory Univ, Sch Med, Dept Pathol, Atlanta, GA 30322 USA

[3] Johns Hopkins Med Inst, Wilmer Inst, Baltimore, MD 21205 USA

[4] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21205 USA

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 2004年 / 137卷 / 03期

关键词：

D O I：

10.1016/j.ajo.2003.09.042

中图分类号：

R77 [眼科学];

学科分类号：

100212 [眼科学];

摘要：

PURPOSE: To review clinicopathologic findings of choroidal neovascularization (CNV) in a historical frame, work with emphasis on pathobiology and correlation with treatment. DESIGN: Selective literature review combined with authors' experience. RESULTS: Choroidal neovascularization represents a stereotypic, nonspecific response to a specific stimulus. Although CNV differs among patients, the general growth patterns are subretinal pigment epithelium (type 1), subretinal (type 2), or combined. Choroidal neovascularization occurs over time in dynamic stages of initiation, active and involutional. Treatments are now being designed based on modem understanding of CNV growth. CONCLUSIONS: Progress continues to be made concerning understanding the pathobiology and treatment of CNV. (C) 2004 by Elsevier Inc. All rights reserved.

引用

页码：496 / 503

页数：8

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