Chemical constituents of Ligularia virgaurea and its diversity in southwestern Sichuan of China

被引：74

作者：

Tori, M ^{[1
]}

Honda, K

Nakamizo, H

Okamoto, Y

Sakaoku, M

Takaoka, S

Gong, X

Shen, YM

Kuroda, C

Hanai, R

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan

[2] Chinese Acad Sci, Kunming Inst Bot, Kunming 654204, Peoples R China

[3] Rikkyo Univ, Dept Chem, Toshima Ku, Tokyo 1718501, Japan

[4] Rikkyo Univ, Dept Life Sci, Toshima Ku, Tokyo 1718501, Japan

来源：

TETRAHEDRON | 2006年 / 62卷 / 20期

基金：

日本学术振兴会;

关键词：

Ligularia virgaurea; sesquiterpene; furanoeremophilane; atpB-rbcL; ITS; diversity;

D O I：

10.1016/j.tet.2006.02.078

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Chemical constituents of root extract and the nucleotide sequences of the atpB-rbcL intergenic region and the internal transcribed spacers (ITSs) of the ribosomal RNA gene were studied for Ligularia virgaurea var. virgaurea collected in southwestern Sichuan Province of China. Eleven samples were collected. Four of them were found to contain four new furanoeremophilanes, virgaurenones A-D, as well as a new cremophilanolide, virgaurenolide A. The other samples contained different furanoeremophilanes and their derivatives including nor-type of compounds, two of which were new. Diversity was found to be present in the nucleotide sequences as well. The chemical composition was found to be correlated with the ITS variation but not with the geographic distribution of the samples. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：4988 / 4995

页数：8

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