Novel nucleotide-calixarene conjugates via phosphoester linkage

被引：16

作者：

Consoli, GML ^{[1
]}

Granata, G ^{[1
]}

Galante, E ^{[1
]}

Cunsolo, F ^{[1
]}

Geraci, C ^{[1
]}

机构：

[1] CNR, Ist Chim Biomol, I-95028 Valverde, CT, Italy

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 19期

关键词：

calixarene; nucleotide; assembly; molecular recognition;

D O I：

10.1016/j.tetlet.2006.03.043

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Calix[4]arenes bearing thymine, adenine, cytosine, guanine 2'-deoxynucleotide residues have been synthesized following the phosphoramidite chemistry. Hybrid Compounds 2a-d and 3a-d represent the first example of nucleotides linked to the calixarene lower rim by a phosphoester bond. Preliminary studies about their assembling in apolar solvent and host properties toward biologically interesting guests are also reported. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3245 / 3249

页数：5

共 29 条

[1] Highly selective recognition of thymidine mono- and diphosphate nucleotides in aqueous solution by ditopic receptors zinc(II)-bis(cyclen) complexes (cyclen 1,4,7,10-tetraazacyclododecane) [J].