Diagnosis and Management of Alcoholic Hepatitis

被引：34

作者：

Sohail, Umair ^{[2
]}

Satapathy, Sanjaya K. ^{[1
]}

机构：

[1] Univ Tennessee, Hlth Sci Ctr, Methodist Univ Hosp, Transplant Inst,Dept Surg, Memphis, TN 38104 USA

[2] Univ Tennessee, Hlth Sci Ctr, Memphis, TN 38104 USA

来源：

CLINICS IN LIVER DISEASE | 2012年 / 16卷 / 04期

关键词：

Alcoholic hepatitis; Aminotransferases; Maddrey's discriminant function; Liver biopsy; Steroids in alcoholic hepatitis; Enteral nutrition in alcoholic hepatitis; Pentoxifylline; Liver transplantation; CARBOHYDRATE-DEFICIENT TRANSFERRIN; RANDOMIZED CONTROLLED-TRIAL; GAMMA-GLUTAMYL-TRANSFERASE; PLACEBO-CONTROLLED TRIAL; MEAN CORPUSCULAR VOLUME; SHORT-TERM SURVIVAL; LIVER-DISEASE; DOUBLE-BLIND; CIRRHOTIC-PATIENTS; ENTERAL NUTRITION;

D O I：

10.1016/j.cld.2012.08.005

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Alcoholic hepatitis is a form of severe, cholestatic liver disease that results from consumption of large amount of alcohol during a sustained period of time in a subset of alcoholics. Symptoms could be mild and nonspecific to more severe. The diagnosis of alcoholic hepatitis can be made with a thorough history, physical examination, and review of laboratory results. Liver biopsy is confirmatory but generally not indicated for the diagnosis. Abstinence is the key form of therapeutic intervention. Despite variable results in clinical trials, corticosteroids and pentoxifylline seem to provide moderate survival benefit. Liver transplantation in acute alcoholic hepatitis is contentious.

引用

页码：717 / +

页数：21

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