Impairments in Cognition Across the Spectrum of Psychiatric Disorders: Evidence From a Swedish Conscript Cohort

被引:45
作者
David, Anthony S. [1 ]
Zammit, Stanley [2 ]
Lewis, Glyn [3 ]
Dalman, Christina [4 ]
Allebeck, Peter [5 ]
机构
[1] Kings Coll London, Inst Psychiat, Sect Cognit Neuropsychiat, London SE5 8AF, England
[2] Univ Wales Hosp, Dept Psychol Med, Cardiff CF14 4XN, S Glam, Wales
[3] Univ Bristol, Div Psychiat, Bristol, Avon, England
[4] Stockholm Ctr Publ Hlth, Dept Psychiat Epidemiol, Stockholm, Sweden
[5] Karolinska Inst, Dept Social Med, Stockholm, Sweden
关键词
IQ; psychosis; cognition; premorbid;
D O I
10.1093/schbul/sbn028
中图分类号
R749 [精神病学];
学科分类号
100205 [精神病与精神卫生学];
摘要
It is well established that cognitive deficits are an almost invariable component of the schizophrenia syndrome. Much less is known about the association of cognitive deficits and the range of psychiatric disorders. The current study made use of a Swedish conscript cohort which included an IQ assessment and full psychiatric evaluation at conscription of all 18- to 19-year-old males. It was found that reduced intellectual functioning was found in association with psychosis and neurotic disorders including depression, personality disorders, alcoholism, and drug dependence. The effect was particularly strong for alcoholism. This presumably represents a combination of premorbid deficits (as demonstrated in those who developed schizophrenia some years later) plus coincident impairments. The direction of causality of this latter association is likely to be both forward and reverse. Different cognitive subtests showed varied strengths of association: "mechanical ability/knowledge," which might reflect planning and reasoning more than the other subtests, had the strongest effect. Cognitive deficits are widespread in psychiatric disorders and should be taken into account in clinical interactions.
引用
收藏
页码:1035 / 1041
页数:7
相关论文
共 25 条
[1]
[Anonymous], GLOSS MENT DIS GUID
[2]
Young cases of schizophrenia identified in a national inpatient register - Are the diagnoses valid? [J].
Dalman, C ;
Broms, J ;
Cullberg, J ;
Allebeck, P .
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY, 2002, 37 (11) :527-531
[3]
IQ and risk for schizophrenia: a population-based cohort study [J].
David, AS ;
Malmberg, A ;
Brandt, L ;
Allebeck, P ;
Lewis, G .
PSYCHOLOGICAL MEDICINE, 1997, 27 (06) :1311-1323
[4]
CHILDHOOD ANTECEDENTS OF SCHIZOPHRENIA AND AFFECTIVE-ILLNESS - SOCIAL-ADJUSTMENT AT AGES 7 AND 11 [J].
DONE, DJ ;
CROW, TJ ;
JOHNSTONE, EC ;
SACKER, A .
BRITISH MEDICAL JOURNAL, 1994, 309 (6956) :699-703
[5]
Executive cognitive functioning and aggressive behavior in preadolescent boys at high risk for substance abuse/dependence [J].
Giancola, PR ;
Martin, CS ;
Tarter, RE ;
Pelham, WE ;
Moss, HB .
JOURNAL OF STUDIES ON ALCOHOL, 1996, 57 (04) :352-359
[6]
JONES P, 1994, LANCET, V334, P1393
[7]
KRISTJANSSON E, 1986, NORD PSYKIATR TIDSSK, V43, P229
[8]
SCHIZOPHRENIA AND CITY LIFE [J].
LEWIS, G ;
DAVID, A ;
ANDREASSON, S ;
ALLEBECK, P .
LANCET, 1992, 340 (8812) :137-140
[9]
Lishman W.A., 1998, Organic Psychiatry, V3rd ed.
[10]
MACCABE JH, 2008, PSYCHOL MED IN PRESS