ArrayExpress update-from an archive of functional genomics experiments to the atlas of gene expression

被引：287

作者：

Parkinson, Helen ^{[1
]}

Kapushesky, Misha ^{[1
]}

Kolesnikov, Nikolay ^{[1
]}

Rustici, Gabriella ^{[1
]}

Shojatalab, Mohammad ^{[1
]}

Abeygunawardena, Niran ^{[1
]}

Berube, Hugo ^{[2
]}

Dylag, Miroslaw ^{[1
]}

Emam, Ibrahim ^{[1
]}

Farne, Anna ^{[1
]}

Holloway, Ele ^{[1
]}

Lukk, Margus ^{[1
]}

Malone, James ^{[1
]}

Mani, Roby ^{[1
]}

Pilicheva, Ekaterina ^{[1
]}

Rayner, Tim F. ^{[3
]}

Rezwan, Faisal ^{[4
]}

Sharma, Anjan ^{[1
]}

Williams, Eleanor ^{[1
]}

Bradley, Xiangqun Zheng ^{[1
]}

Adamusiak, Tomasz ^{[1
]}

Brandizi, Marco ^{[1
]}

Burdett, Tony ^{[1
]}

Coulson, Richard ^{[1
]}

Krestyaninova, Maria ^{[1
]}

Kurnosov, Pavel ^{[1
]}

Maguire, Eamonn ^{[1
]}

Neogi, Sudeshna Guha ^{[1
]}

Rocca-Serra, Philippe ^{[1
]}

Sansone, Susanna-Assunta ^{[1
]}

Sklyar, Nataliya ^{[1
]}

Zhao, Mengyao ^{[5
]}

Sarkans, Ugis ^{[1
]}

Brazma, Alvis ^{[1
]}

机构：

[1] European Bioinformat Inst, Hinxton CB10 1SD, Cambs, England

[2] Natl Res Council Canada, Inst Informat Technol, Ottawa, ON K1A 0R6, Canada

[3] Univ Cambridge, Cambridge Inst Med Res, Cambridge, England

[4] Univ Hertfordshire, BioComputat Lab, Hatfield AL10 9AB, Herts, England

[5] Wellcome Trust Sanger Inst, Hinxton, England

来源：

NUCLEIC ACIDS RESEARCH | 2009年 / 37卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

PUBLIC REPOSITORY; MICROARRAY DATA; DATABASE; PROFILES; ONTOLOGY; PLATFORM; SERVICE; FORMAT; EBI; TAB;

D O I：

10.1093/nar/gkn889

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ArrayExpress http://www.ebi.ac.uk/arrayexpress consists of three components: the ArrayExpress Repository-a public archive of functional genomics experiments and supporting data, the ArrayExpress Warehouse-a database of gene expression profiles and other bio-measurements and the ArrayExpress Atlas-a new summary database and meta-analytical tool of ranked gene expression across multiple experiments and different biological conditions. The Repository contains data from over 6000 experiments comprising approximately 200 000 assays, and the database doubles in size every 15 months. The majority of the data are array based, but other data types are included, most recently ultra high-throughput sequencing transcriptomics and epigenetic data. The Warehouse and Atlas allow users to query for differentially expressed genes by gene names and properties, experimental conditions and sample properties, or a combination of both. In this update, we describe the ArrayExpress developments over the last two years.

引用

页码：D868 / D872

页数：5

共 21 条

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