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Outbreak of cefozopran (Penicillin, oral cephems, and aztreonam)-resistant Neisseria gonorrhoeae in Japan

被引：56
作者：
Muratani, T
Akasaka, S
Kobayashi, T
Yamada, Y
Inatomi, H
Takahashi, K
Matsumoto, T
机构：
[1] Univ Occupat & Environm Hlth, Sch Med, Dept Urol, Yahatanishi Ku, Kitakyushu, Fukuoka 8078555, Japan
[2] Kyurin Co, Yahatanishi Ku, Kitakyushu, Fukuoka, Japan
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 12期
关键词：
D O I：
10.1128/AAC.45.12.3603-3606.2001
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We have previously reported that the Neisseria gonorrhoeae isolates from clinical failure cases treated with cefdinir and aztreonam, beta -lactams exhibited high MICs. These resistant isolates were clearly separated from the isolates exhibiting a low level of resistance to P-lactams as shown by the MIC distribution of cefozopran. Restriction fragment length polymorphism DNA typing revealed that the outbreak of cefozopran-resistant isolates in Kitakyushu, Japan, occurred as a result of clonal spread.
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页码：3603 / 3606
页数：4
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