The double life of aconitase

被引：14

作者：

Artymiuk, PJ ^{[1
]}

Green, J ^{[1
]}

机构：

[1] Univ Sheffield, Dept Mol Biol & Biotechnol, Krebs Inst, Sheffield S10 2TN, S Yorkshire, England

来源：

STRUCTURE | 2006年 / 14卷 / 01期

关键词：

D O I：

10.1016/j.str.2005.12.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this issue of Structure, Volbeda, Fontecilla-Camps, and colleagues (Dupuy et al., 2006) present the first structure of a eukaryotic cytoplasmic aconitase (cAcn). Their work casts new light on the crucial RNA binding function of some of the members of the aconitase superfamily.

引用

页码：2 / 4

页数：3

共 13 条

[1] Structure and dynamics of the iron responsive element RNA: Implications for binding of the RNA by iron regulatory binding proteins [J].

Addess, KJ ;

Basilion, JP ;

Klausner, RD ;

Rouault, TA ;

Pardi, A .

JOURNAL OF MOLECULAR BIOLOGY, 1997, 274 (01) :72-83

[2] THE IRON-RESPONSIVE ELEMENT-BINDING PROTEIN - LOCALIZATION OF THE RNA-BINDING SITE TO THE ACONITASE ACTIVE-SITE CLEFT [J].

BASILION, JP ;

ROUAULT, TA ;

MASSINOPLE, CM ;

KLAUSNER, RD ;

BURGESS, WH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (02) :574-578

[3] Crystal structure of human iron regulatory protein 1 as cytosolic aconitase [J].

Dupuy, J ;

Volbeda, A ;

Carpentier, P ;

Darnault, C ;

Moulis, JM ;

Fontecilla-Camps, JC .

STRUCTURE, 2006, 14 (01) :129-139

[4] Iron regulatory proteins and the molecular control of mammalian iron metabolism [J].

Eisenstein, RS .

ANNUAL REVIEW OF NUTRITION, 2000, 20 :627-662

[5] The aconitase family: Three structural variations on a common theme [J].

Gruer, MJ ;

Artymiuk, PJ ;

Guest, JR .

TRENDS IN BIOCHEMICAL SCIENCES, 1997, 22 (01) :3-6

[6]

GUO B, 1994, J BIOL CHEM, V269, P24252

[7] Identification of RNA-binding surfaces in iron regulatory protein-1 [J].

Kaldy, P ;

Menotti, E ;

Moret, R ;

Kühn, LC .

EMBO JOURNAL, 1999, 18 (21) :6073-6083

[8] PURIFICATION AND CHARACTERIZATION OF CYTOSOLIC ACONITASE FROM BEEF-LIVER AND ITS RELATIONSHIP TO THE IRON-RESPONSIVE ELEMENT BINDING-PROTEIN [J].

KENNEDY, MC ;

MENDEMUELLER, L ;

BLONDIN, GA ;

BEINERT, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (24) :11730-11734

[9] CRYSTAL-STRUCTURES OF ACONITASE WITH ISOCITRATE AND NITROISOCITRATE BOUND [J].

LAUBLE, H ;

KENNEDY, MC ;

BEINERT, H ;

STOUT, CD .

BIOCHEMISTRY, 1992, 31 (10) :2735-2748

[10] Iron metabolism and the IRIE/IRP regulatory system - An update [J].

Pantopoulos, K .

REDOX-ACTIVE METALS IN NEUROLOGICAL DISORDERS, 2004, 1012 :1-13

← 1 2 →