1-methyl-1-(2,4-dinitrophenyl)hydrazine as a new reagent for the HPLC determination of aldehydes

被引：36

作者：

Buldt, A ^{[1
]}

Karst, U ^{[1
]}

机构：

[1] UNIV MUNSTER,INST ANORGAN CHEM,ABT ANALYT CHEM,D-48149 MUNSTER,GERMANY

来源：

ANALYTICAL CHEMISTRY | 1997年 / 69卷 / 17期

关键词：

D O I：

10.1021/ac970146p

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The synthesis and first application of an N-alkylated hydrazine reagent for the HPLC determination of aldehydes and ketones is described. 1-Methyl-1-(2,4-dinitrophenyl)hydrazine (MDNPH) reacts with aldehydes to give the corresponding hydrazones in the presence of an acid as catalyst. In contrast to other hydrazine reagents, MDNPH is oxidized by both ozone and nitrogen dioxide quantitatively to N-methyl-2,4-dinitroaniline (MDNA), which can be separated from the hydrazones of the lower aldehydes by means of HPLC. Unexpected elution orders are observed for the 1-methyl-1-(2,4-dinitrophenyl)hydrazones compared to those of 2,4-dinitrophenylhydrazones. Dual-wavelength detection is employed as a means for identification of different groups of the hydrazones and MDNA.

引用

页码：3617 / 3622

页数：6

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