NMR measurements of diffusion in concentrated samples: avoiding problems with radiation damping

被引：19

作者：

Connell, MA

Davis, AL

Kenwright, AM

Morris, GA

机构：

[1] Univ Manchester, Dept Chem, Manchester M13 9PL, Lancs, England

[2] Pfizer Ltd, Global Res & Dev, Sandwich CT13 9NJ, Kent, England

[3] Univ Durham, Dept Chem, Durham DH1 3LE, England

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2004年 / 378卷 / 06期

基金：

英国工程与自然科学研究理事会;

关键词：

diffusion; radiation damping; DOSY; water; siloxanes;

D O I：

10.1007/s00216-003-2387-y

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Pulsed field gradient spin echo NMR is generally the method of choice for diffusion measurements on liquid samples. With modem high field instruments, however, severe problems can arise when it is applied to samples with very high proton concentrations because of the presence of radiation damping. The problems may be greatly reduced by a suitable choice of experimental parameters, in particular the use of modified stimulated echo pulse sequences with a reduced flip angle for the first pulse.

引用

页码：1568 / 1573

页数：6

共 19 条

[1]

ABRAGAM A, 1961, PRINCIPLES NUCLEAR M, P73

[2] THE BEHAVIOR OF MULTIPLET SIGNALS UNDER RADIATION DAMPING CONDITIONS .1. CLASSICAL EFFECTS [J].