Protein C and S deficiency

被引：35

作者：

Nizzi, FA ^{[1
]}

Kaplan, HS ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75235 USA

来源：

SEMINARS IN THROMBOSIS AND HEMOSTASIS | 1999年 / 25卷 / 03期

关键词：

protein C; protein S; thrombophilia; protein C deficiency; protein S deficiency; thrombosis;

D O I：

10.1055/s-2007-994930

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Protein C and S deficiency states predispose affected individuals to thrombosis, especially venous thrombosis of the lower extremities, usually beginning in the teenage years. Treatment of these patients is generally with oral anticoagulation, following initial heparinization. The classification of the deficiency states is dependent upon determination of the quantity and functional activity of either protein.

引用

页码：265 / 272

页数：8

共 64 条

[1]

Adcock DM, 1997, AM J CLIN PATHOL, V108, P434

[2]

Aiach M, 1996, HAEMOSTASIS, V26, P9

[3] INCREASED RISK OF VENOUS THROMBOSIS IN CARRIERS OF HEREDITARY PROTEIN-C DEFICIENCY DEFECT [J].

ALLAART, CF ;

POORT, SR ;

ROSENDAAL, FR ;

REITSMA, PH ;

BERTINA, RM ;

BRIET, E .

LANCET, 1993, 341 (8838) :134-138

[4] NEW DIRECT ASSAY OF FREE PROTEIN-S ANTIGEN USING 2 DISTINCT MONOCLONAL-ANTIBODIES SPECIFIC FOR THE FREE-FORM [J].

AMIRAL, J ;

GROSLEY, B ;

BOYERNEUMANN, C ;

MARFAINGKOKA, A ;

PEYNAUDDEBAYLE, E ;

WOLF, M ;

MEYER, D .

BLOOD COAGULATION & FIBRINOLYSIS, 1994, 5 (02) :179-186

[5] MUTATION IN BLOOD-COAGULATION FACTOR-V ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C [J].

BERTINA, RM ;

KOELEMAN, BPC ;

KOSTER, T ;

ROSENDAAL, FR ;

DIRVEN, RJ ;

DERONDE, H ;

VANDERVELDEN, PA ;

REITSMA, PH .

NATURE, 1994, 369 (6475) :64-67

[6] HYPERCOAGULABILITY AND THROMBOSIS [J].

BICK, RL .

MEDICAL CLINICS OF NORTH AMERICA, 1994, 78 (03) :635-665

[7] A NEW METHOD FOR THE ESTIMATION OF PROTEIN-C BY ELISA [J].

BOYER, C ;

ROTHSCHILD, C ;

WOLF, M ;

AMIRAL, J ;

MEYER, D ;

LARRIEU, MJ .

THROMBOSIS RESEARCH, 1984, 36 (06) :579-589

[8]

BROEKMANS AW, 1987, THROMB HAEMOSTASIS, V57, P20

[9]

CASELLA JF, 1988, LANCET, V1, P435

[10] RECURRENT VENOUS THROMBOEMBOLISM IN PATIENTS WITH A PARTIAL DEFICIENCY OF PROTEIN-S [J].

COMP, PC ;

ESMON, CT .

NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (24) :1525-1528

← 1 2 3 4 5 6 7 →